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Lyvispah (baclofen) was approved for the treatment of spasticity resulting from MS by:

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The active ingredient in Lyvispah, baclofen, is used to help relax certain muscles in your body. It helps relieve spasticity (cramping, and tightness of muscles) caused by conditions such as MS or certain injuries to the spine. It can also reduce pain and improve muscle movement.

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Gabapentin interacts negatively with other antidepressants, including selective serotonin